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. Author manuscript; available in PMC: 2012 Sep 20.
Published in final edited form as: Cancer Metastasis Rev. 2011 Dec;30(3-4):419–435. doi: 10.1007/s10555-011-9300-5

Fig. 2.

Fig. 2

MicroRNA sequences and location of miR-200 family, miR-143/145, miR-101, and miR-16-1/15a. miRNA families consist of miRNAs with similar mature sequences and are either transcribed together as part of a polycistronic pri-miRNA or are located at distinct sites throughout the genome. The chromosomal location and distance between clustered miRNAs of the four classes of miRNAs identified to target the genes that mediate PGE2 synthesis and function are indicated. In the mature miRNA sequences, red text indicates regions of sequence homology within each miRNA family. MiR-3671 is located approximately 600 nucleotides upstream of miR-101; however, miR-3671 has not been validated to be co-expressed with miR-101 or was identified to target any genes in the PGE2 pathway