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. 2012 Sep 20;7(9):e45572. doi: 10.1371/journal.pone.0045572

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© 2012 Avella et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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A: Gonad type percentage of 10 zebrafish from control (c) and probiotic (p) groups at 3, 6 and 9 weeks post fertilization – wpf. Assay was run in triplicate. B: Normal gonad development; progression from undifferentiated gonad, to ovary, altered ovary and testis. C: representative pictures of ovary, altered ovary and testis prematurely observed in probiotic treated fish at 3 weeks post fertilization. Legend: go, gonocyte; do, degenerating oocytes; sc, spermatocyst; I, stage I oocyte; II, stage II oocyte; scale bars 50 µm.