Table 2. Mechanical parameters of fibers from Tg(ACTA1)Asp286Gly and wild-type mice during steady-state isometric contractions.
| Tg(ACTA1)Asp286Gly | Wild-type | |
| Maximal force (kPa) | 124.20±12.40# (n = 34) | 221.80±10.70 (n = 35) |
| Active stiffness (kPa.% L0−1) | 51.60±5.70# (n = 22) | 112.10±15.70 (n = 24) |
| Rigor stiffness (kPa.% L0−1) | 161.20±16.10 (n = 22) | 187.40±14.50 (n = 24) |
| f xb (A.U.) | 0.24±0.03# (n = 22) | 0.42±0.04 (n = 24) |
| y0 * (% L0) | 1.01±0.07 (n = 20) | 1.07±0.23 (n = 20) |
| Cf+Ce (% L0.MPa−1) | 6.50±1.30 (n = 20) | 5.30±0.90 (n = 20) |
| k tr (s−1) | 52.90±5.30 (n = 12) | 41.70±2.90 (n = 11) |
| V0 (ML.s−1) | 5.80±0.70# (n = 10) | 3.90±0.80 (n = 10) |
Due to a type IIb muscle fiber predominance in the EDL muscles, the comparison was restricted to cells expressing the type IIb MyHC isoform. # indicates a significant difference when compared with wild-type animals (p<0.05). For each parameter, n represents the number of tested fibers.