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. 2012 Sep 20;7(9):e45562. doi: 10.1371/journal.pone.0045562

Figure 3. Expression of IL-8, but not CXCR2, is elevated in human glioblastoma.

Figure 3

A–D) Retrospective gene array analysis was performed using the REMBRANDT (Repository of Molecular Brain Neoplasia Data) collection from National Cancer Institute (NCI) and the National Institute of Neurological Disorders and Stroke (NINDS). Median expression intensities are reported as a graph for IL-8 and CXCR2 genes in (A) and for VEGF-A, MCP-1 (Monocyte Chemotactic Protein), Ang-1 (angiopoeitin) and FGF-2 (fibroblast growth factor) genes in (B), on Non T: non tumor tissue; Astro: astrocytoma; GBM: glioblastoma multiforme; Oligo: oligodendroglioma. C–D) Probability of survival is shown for GBM divided into groups with either high (3-fold increase) or low (3-fold decrease) gene expression of IL-8 (C) and CXCR2 (D). p values (p) are provided. N indicates sample number in each category. All data were obtained using the REMBRANDT database accessed on June 11th 2012.