Figure 6. Increased levels of the neutrophil attractant chemokines KC and MIP-2 in WT male mouse sera upon MCMV infection.

WT or TLR9^−/− male and female mice were infected i.p. with 1×10⁵ PFU MCMV and sera were collected 36 h after infection. Upon MCMV infection, WT male mice produced statistically significant higher levels of KC and MIP-2 than WT female or TLR9^−/− male and female mice, while the MCP-1 levels were higher in WT mice compared to TLR9^−/− mice. KC, MIP-2 and MCP-1 protein levels were measured by CBA flex or ELISA. Data are representative of four independent experiments. *p<0.05, **p<0.01 and ***p<0.001.