Table 1. Relative retinal mRNA levels in R227W and compound mutants at E12.5.
R227W | R227W; Mitfmi/+ | R227W, p27+/− | |
pan- Mitf | 1.00±0.12 | 0.15±0.08*** | 0.52±0.05** ; # |
D-Mitf | 1.00±0.07 | 0.09±0.04** | 0.27±0.05*** ; # |
A-Mitf | 1.00±0.12 | 0.14±0.06** | 1.69±0.29## |
H-Mitf | 1.00±0.11 | 0.07±0.03*** | 0.78±0.23# |
B-Mitf | 1.00±0.09 | 0.80±0.40 | 0.92±0.20 |
J-Mitf | 1.00±0.20 | 0.19±0.06** | 1.12±0.29## |
Otx1 | 1.00±0.11 | 0.37±0.13* | 0.45±0.04** |
P≤0.05;
P≤0.01;
P≤0.001 (compared to R227W).
P≤0.05;
P≤0.01 (compared to R227W; Mitf mi/+).