Figure 5. Simulations of multiple Tsr dimer models in a biologically realistic membrane in the form of ∼70 nm diameter lipid vesicles.

Helices are rendered as green curved tubes, lipids are in grey. A Tsr dimers at t = 0 and 1.5 µs, and B Tsr trimer-of-dimers at t = 0 and 1 µs. The Tsr dimers can be observed to make a wide variety of interdimer contacts, whereas the trimers-of-dimers form only limited interactions with one another.