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Domain structure of CGFS monothiol Grxs from E. coli, S. cerevisiae, S. pombe, and H. sapiens. The Trx-like domains and Grx-like domains are shown as purple and blue boxes, respectively. The conserved cysteines in the active sites of the Trx and Grx domains are numbered and shown in yellow. Predicted or known mitochondrial targeting signals are shown as pink boxes.
