Table 1.
All subjects (n = 35) | |||||
---|---|---|---|---|---|
Preparation | Linoleic acid from safflower oil | Tonalin® (50:50 mix) | Cis-9, trans-11 CLA | Trans-10, cis-12 CLA | p-Value within group |
Anthropometry | |||||
Weight | 84.2 (±2.0) | 84.2 (±2.0) | 84.1 (±2.0) | 84.0 (±2.0) | 0.851 |
BMI (kg/m2) | 26.1 (±0.5) | 26.1 (±0.4) | 26.0 (±0.4) | 26.0 (±0.5) | 0.900 |
Waist (cm) | 102.1 (±1.5) | 102.1 (±1.6) | 102.3 (±1.5) | 101.3 (±1.5) | 0.172 |
Hip (cm) | 104.8 (±1.0) | 104.8 (±1.0) | 104.8 (±1.0) | 104.0 (±1.0) | 0.824 |
Waist/hip ratio | 0.97 (±0.01) | 0.97 (±0.01) | 0.98 (±0.01) | 0.97 (±0.01) | 0.645 |
Fasting values | |||||
Plasma glucose (mg/dl) | 96.5 (±1.4) | 98.2 (±1.5) | 97.5 (±1.5) | 96.5 (±1.4) | 0.487 |
Serum insulin (μU/ml) | 12.5 (±1.0) | 12.9 (±1.0) | 12.5 (±1.1) | 12.2 (±1.0) | 0.898 |
HOMA-IR (μU/ml*mg/dl/405 | 3.0 (±0.3) | 3.2 (±0.2) | 3.1 (±0.3) | 2.9 (±0.3) | 0.828 |
Triacylglycerols (mg/dl) | 127.0 (±10.1) | 124.4 (±10.8) | 119.1 (±8.9) | 124.7 (±10.6) | 0.787 |
Adiponectin (ng/ml) | 7,334 (±467) | 7,452 (±497) | 7,681 (±493) | 7,172 (±479) | 0.152 |
Plasma leptin (pg/ml) | 5,054 (±532)a | 4,732 (±482)a,b | 5,027 (±559)a | 4,425 (±528)b | 0.054 |
Postprandial values | |||||
Glucose AUC (mg/dl) | 483.0 (±8.9) | 484.5 (±8.3) | 472.3 (±7.9) | 447.6 (±23.4) | 0.111 |
Insulin AUC (μU/ml) | 155.6 (±11.3)b | 137.5 (±10.2)a | 143.6 (±10.8)a | 157.2 (±13.0)b | 0.054 |
HOMA-IR AUC | 189.0 (±14.8)a,b | 167.3 (±13.4)a | 169.2 (±13.7)a | 195.4 (±19.5)b | 0.025* |
Triacylglycerols (mg/dl) | 1,661 (±130) | 1,621 (±126) | 1,536 (±111) | 1,666 (±135) | 0.445 |
Adiponectin 5 h (ng/ml) | 7,364 (±471) | 7,401 (±467) | 7,540 (±484) | 7,067 (±470) | 0.161 |
Leptin AUC (pg/ml) | 39,092 (±4,060) | 38,220 (±3,934) | 39,502 (±4,386) | 36,467 (±4,523) | 0.320 |
All values are expressed as mean ± SEM
CLA conjugated linoleic acid, BMI body mass index
* Significant differences between intervention periods in overall test (p ≤ 0.05; MANOVA). Duncan′s post hoc test was used to describe where the differences between intervention groups appeared. Means that are significantly different from others are marked as unlike letters. p-Value ≤ 0.1 was seen as a trend. To demonstrate where differences occurred in analyses, means were marked as unlike letters, too. For details of diets, see research design and methods