Table 3.
Change in Adipose Tissue Distribution from Baseline to Week 48
| |
DRV/r n=34 |
ATV/r n=31 |
|
||
|---|---|---|---|---|---|
| BL | Change from BL to week 48 | BL | Change from BL to week 48 | Difference in mean change between arms (95% CI) | |
| Abdomen | n=29 | n=20 | n=30 | n=24 | |
| TAT, mean (SD), cm2 | 258.7 (89.38) | 24.2 (98.40) | 285.1 (120.80) | 29.4 (38.32) | −5.20 (−49.19, 38.79) |
| VAT, mean (SD), cm2 | 97.6 (47.10) | −0.6 (49.20) | 102.5 (44.60) | 3.8 (24.48) | −4.38 (−27.43, 18.67) |
| SAT, mean (SD), cm2 | 161.1 (74.06) | 24.8 (56.50) | 182.7 (108.37) | 25.6 (28.20) | −0.82 (−27.31, 25.67) |
| VAT/SAT ratio, mean (SD) | 0.50 (0.281) | 0.00 (0.135) | 0.53 (0.289) | −0.04 (0.104) | 0.04 (−0.03, 0.11) |
| Mid-thigh | n=29 | n=21 | n=27 | n=21 | |
| PAT, mean (SD), cm2 | 55.4 (25.74) | 7.0 (17.32) | 61.0 (38.06) | −1.9 (9.53) | 8.88 (0.16, 17.60) |
DRV/r, darunavir/low-dose ritonavir; ATV/r, atazanavir/low-dose ritonavir; CI, confidence interval; BL, baseline; TAT, total adipose tissue; SD, standard deviation; VAT, visceral adipose tissue; SAT, subcutaneous adipose tissue; PAT, peripheral adipose tissue.