TABLE 2 .
Effects of siRNA knockdowns of Pols on TLS opposite a cis-syn TT dimer located on the leading- or lagging-strand DNA template of SV40 plasmid carried in XPA human fibroblasts
| siRNA | Leading strand |
Lagging strand |
||||
|---|---|---|---|---|---|---|
| No. of kan+ colonies | No. of blue colonies among kan+ colonies |
TLS (%) | No. of kan+ colonies | No. of blue colonies among kan+ colonies |
TLS (%) | |
| NC | 421 | 150 | 35.6 | 326 | 105 | 32.2 |
| Polη | 340 | 57 | 16.8 | 368 | 52 | 14.1 |
| Polι | 486 | 169 | 34.8 | 456 | 136 | 29.8 |
| Polκ | 429 | 102 | 23.8 | 322 | 69 | 21.4 |
| Rev3 | 321 | 72 | 22.4 | 416 | 86 | 20.7 |
| Rev7 | 360 | 77 | 21.4 | 425 | 91 | 21.4 |