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. 2012 Mar;22(1):23–27.

Table 1.

Characteristics of patients with Familial Mediterranean Fever and result of treatment with Dapsone

SEX Age Before colchicine After colchicine After dapsone
Period of attack Duration Severity Age at onset of colchicine Dosage of colchicine Period of pain Duration Severity Dosage of dapsone Lengthy of dapsone therapy Number of attacks Severity
M 6yr 7-10 days 72 - 96 hr 10 1. 5yr 0. 5mg BID 2 times in 4. 5 years 3 -4 hr 10 30 mg daily 3Mo & 17day 1time 10
10
F 8yr 2 day 1 -2 hr 10 3. 5yr 0. 5mg BID 2-3 times in month 0. 5 – 1 hr 7 50mg daily 3Mo & 17day 1time 10
F 5yr At first : 30 days Then: 3-8 days o. 5 – 24 hr 10 1. 5yr 0. 5mg BID NO NO NO 25mg daily 7 day 1time 10
10
F 7yr Variable 3 -12 hr 9 2yr 0. 5mg daily NO NO NO 50mg daily 14 day 2times 10
10
M 6yr 7 days 24 hr 7 - 8 2yr 0. 5mg daily 2 times in 4 years 12 hr 7 - 8 30 mg daily < 7 day NO NO
M 10yr 20 -30 days 24 hr 9 4yr 0. 5mg BID NO NO NO 50mg daily 9 Mo NO NO
NO
F 7yr 15 – 20 days 3 -4 hr 10 5yr 0. 5mg daily 2 – 3/month 72 hr 3 50mg daily 10 Mo NO NO
F 7yr 14 days More than 96 hr 10 4yr 0. 5mg BID NO NO NO 50mg daily 6Mo & 8 day NO NO
M 8yr 14 days 48hr 10 6yr 0. 5mg daily 2 times in 2 years 48 – 72 hr 5 - 6 50mg daily 9Mo NO NO
F 9yr 7 days 8 -9 hr 6 2yr 0. 5mg BID No / pain Fever occasionally NO NO 50mg daily 9Mo No attack* NO
*

but some febrile attacks without abdominal pain M: Male / F: Female