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. Author manuscript; available in PMC: 2012 Sep 21.
Published in final edited form as: Biopolymers. 2011;96(5):604–616. doi: 10.1002/bip.21599

Scheme 1.

Scheme 1

General route for the synthesis of peptoids 1–4.a

a Reagents and conditions: HNR2 = piperidine or dimethylamine hydrochloride, TEA = triethylamine, CH2Cl2 = dichloromethane, H2NR′ = O-benzyl hydroxylamine hydrochloride or aniline, DIPEA = diisopropylethylamine, DMF = N,N-dimethylformamide, rt = room temperature, AcCl = acetyl chloride.