Table 4.
Correlations of some phospho-ERα epitopes with progesterone receptor (PR) expression and total ERα
Marker | P-S104/6 | P-S118 | P-S167 | P-S282 | P-S294 | P-T311 | P-S559 | ER (LBA and/or IHC) | PR (LBA) |
---|---|---|---|---|---|---|---|---|---|
P-S104/6 | P < 0.0001 | P < 0.0001 | P = 0.0005 | P = 0.0004 | |||||
r = 0.38 | r = 0.4 | r = 0.2 | r = 0.2 | ||||||
N = 293 | N = 280 | N = 301 | N = 301 | ||||||
P-S118 | P < 0.0001 | P = 0.008 | P= 0.02 | P < 0.0001 | P < 0.0001 | P = 0.0017 | |||
r = 0.46 | r = 0.14 | r = 0.12 | r = 0.3 | r = 0.35 | r = 0.16 | ||||
N = 360 | N = 340 | N = 363 | N = 355 | N = 355 | N = 369 | ||||
P-S167 | P < 0.0001 | P = 0.0012 | P = 0.0032 | P < 0.0001 | |||||
r = 0.46 | r = 0.16 | r = 0.15 | r = 0.27 | ||||||
N = 360 | N = 391 | N = 367 | N = 379 | ||||||
P-S282 | P = 0.008 | P < 0.0001 | P < 0.0001 | ||||||
r = 0.14 | r = 0.31 | r = 0.23 | |||||||
N = 340 | N = 367 | N = 346 | |||||||
P-S294 | P = 0.02 | P = 0.0012 | P < 0.0001 | P = 0.0022 | |||||
r = 0.12 | r = 0.16 | r = 0.31 | r = 0.16 | ||||||
N = 363 | N = 391 | N = 367 | N = 373 | ||||||
P-T311 | P < 0.0001 | P < 0.0001 | P = 0.0001 | P = 0.033 | |||||
r = 0.38 | r = 0.34 | r = 0.22 | r = 0.11 | ||||||
N = 293 | N = 370 | N = 405 | N = 405 | ||||||
P-S559 | P < 0.0001 | P < 0.0001 | P = 0.0032 | P < 0.0001 | P = 0.0022 | P < 0.0001 | P < 0.0001 | ||
r = 0.4 | r = 0.3 | r = 0.15 | r = 0.23 | r = 0.16 | r = 0.34 | r = 0.24 | |||
N = 280 | N = 355 | N = 367 | N = 346 | N = 373 | N = 370 | N = 379 |
Associations were assessed by the Spearman's rank correlation test (r)