Table 1.

Clinical studies indicating an association between CSC-related pathways and treatment response

Cancer Type	Gene/Pathway	Prediction	Ref.
Colorectal cancer	CD133	Poor response to fluorouracil-based chemotherapy	[44]
Esophageal cancer	Hedgehog pathway	Poor response to chemo-radiotherapy	[50]
Ewing sarcoma	Wnt pathway	VIDE regimen: tumor regression	[49]
Glioblastoma	CD133 EGFR	Poor survival after radio-chemotherapy	[45]
Head/neck cancer	BMI1	Poor survival after radio-chemotherapy	[46]
NSCLC	BMI1	Poor disease-free survival after adjuvant chemotherapy	[47]
NSCLC	CD133	High expression of drug-resistance genes	[51]
Rectal cancer	CD133	Poor disease-free survival after neoadjuvant chemotherapy	[48]