Table 4. The application of saRNA in urology and andrology.
| Disease | Species | Gene | Trigger RNA | Applications | References |
|---|---|---|---|---|---|
| Prostate cancer | Human | p21 | saRNA | In vitro, in vivo (xenograft) | (2) |
| Human | E-cadherin | saRNA and miRNA | In vitro | (2,6,85) | |
| Human | KLF4 | saRNA | In vitro | (86) | |
| Human | NKX3.1 | saRNA | In vitro, in vivo (xenograft) | (87) | |
| Mouse | Ccnb1 | saRNA and miRNA | In vitro, in vivo (xenograft) | (87,88) | |
| Bladder cancer | Human | p21 | saRNA | In vitro, in vivo (xenograft) | (89,90) |
| Human | E-cadherin | saRNA | In vitro | (91) | |
| Renal cancer | Human | p21 | saRNA | In vitro | (92) |
| ED | Human | VEGF | saRNA | In vitro | (93) |