Table 1.
Mean size (μm) of DIG-dUTP incorporation signals in nuclei of hamster and mouse cells in the presence or absence of Tax or etoposide
| Experimental groups | n | mean size | Standard deviation | |
|---|---|---|---|---|
| 1 |
Mouse embryo fibroblasts (MEFs) |
68 |
1.37 |
0.46 |
| 2 |
MEFs + etoposide 5 μg/ml * |
46 |
1.77 |
1.15 |
| 3 |
MEFs + etoposide 10 μg/ml * |
50 |
2.06 |
0.96 |
| 4 |
CHO |
66 |
1.16 |
0,31 |
| 5 |
CHO + Tax |
50 |
3.81 |
1.74 |
| 6 |
xrs-6 |
56 |
1.99 |
0.82 |
| 7 |
xrs-6 + Tax |
120 |
2.08 |
0.67 |
| 8 |
PKcs+/+ |
38 |
1.43 |
0.51 |
| 9 |
PKcs+/+ + Tax |
70 |
2.28 |
1.05 |
| 10 |
PKcs−/− |
98 |
1.35 |
0.45 |
| 11 |
PKcs−/− + Tax |
150 |
2.35 |
0.99 |
| 12 |
XRCC4+/+ |
77 |
1.63 |
0.69 |
| 13 |
XRCC4+/+ + Tax |
50 |
3.53 |
1.68 |
| 14 |
XRCC4−/− |
175 |
1.74 |
0.67 |
| 15 |
XRCC4−/− + Tax |
48 |
3.39 |
1.12 |
| 16 |
H2AX+/+ |
68 |
1.37 |
0.46 |
| 17 |
H2AX+/+ + Tax |
70 |
2.50 |
0.95 |
| 18 |
H2AX−/− |
65 |
2.01 |
0.76 |
| 19 | H2AX−/− + Tax | 68 | 3.20 | 0.90 |
* = three hours of treatment.
n = number of measured DIG-dUTP incorporation signals.