Table 5.
Patients with carcinoma ex pleomorphic adenoma as primary head and neck cancer
| Author, year | Patient no. | Patient age | Primary site, grade | Primary stage | Intervention for primary site | Location of spinal metastasis | Time frame of spinal metastasis | Signs + symptoms of spinal metastasis | Intervention for spinal metastasis | Outcome | Other metastasis | Mortality | Cause of death |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Thomas, 1965 [30] |
1 |
74 |
Parotid carcinoma ex pleomorphic adenoma |
- |
Excision, removal of recurrences |
T7 |
8 yr |
Weakness, back pain, increased micturition |
Laminectomy |
No response |
None |
9 d |
GI haemorrhage, benign gastric ulcer |
| |
2 |
63 |
Parotid carcinoma ex pleomorphic adenoma |
- |
Excision, adjuvant RT, removal of recurrences |
T8 |
26 yr |
Back pain, complete paralysis |
Laminectomy |
Paralysis persisted, died soon after op |
- |
No time given |
- |
| Manoj-Thomas, 2006 [13] |
3 |
58 |
Parotid carcinoma ex pleomorphic adenoma |
- |
Superficial parotidectomy |
L4 |
7 yr |
Low back pain with radiation to left leg |
RT |
Improved pain. Hypoaesthesia at 18 mo |
Left acetabulum, Lungs |
- |
- |
| Ye, 2007 [12] | 4 | 28 | Submandibular carcinoma ex pleomorphic adenoma | - | - | T10, L3 | 40 yr | Leg weakness | Excision, RT (25 Gy) | Improved, no recurrence on follow-up MRI | Forearm skin, scalp, frontal bone, occipital bone, lungs | - | - |
“RT”: Radiation therapy. “CT”: Chemotherapy. “CR”: Chemoradiation.” Grade”: Greenberg Grade. “Gy”: Gray. “yr”: year(s). “mo”: month(s). “wk”: week(s). “d”: day(s). “-“: Not given.