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. 2012 Sep 21;7(9):e45251. doi: 10.1371/journal.pone.0045251

Figure 10. Morphine Inhibits TTX-resistant Na+ channels.

Figure 10

TTX-resistant Na+ current was examined in the presence of Cs+-containing internal solution (A). 1 µM TTX blocked all TTX-sensitive Na+ channels (A, middle panel), and then morphine (3 µM, A, right panel) was added to assess the effects of the drug on TTX-resistant Na+ current. Current density- voltage analysis (B) showed that TTX-resistance Na+ current is partially inhibited by the addition of 3 µM morphine.