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. 2012 Sep 21;7(9):e45535. doi: 10.1371/journal.pone.0045535

Table 3. Ratio metafeatures clustered with MMSE score.

Metafeature (Gene Symbol. Probe Set ID) Correlation Coefficient Common KEGG Pathways
PPIA.212661_x_at/C3orf60.209177_at 0.884365
PIGO.209998_at/CASK.211208_s_at 0.760958
PURA.213806_at/AJ225093.211835_at 0.673877
PRKCB1.209685_s_at/PTEN.222176_at −0.68675 Phosphatidylinositol signaling system
FOXO1.202724_s_at/ACACA.212186_at −0.78654 Insulin signaling pathway
CASK.211208_s_at/PTEN.222176_at −0.83565 Tight junction
RPL23A.203012_x_at/ATP5C1.213366_x_at −0.83758
CASK.211208_s_at/ATP5C1.213366_x_at −0.86355
ACACA.212186_at/LDHA.200650_s_at −0.87642 Propanoate metabolism
PRKAR2B.203680_at/ACACA.212186_at −0.88001 Insulin signaling pathway
COX6A1.200925_at/ATP5C1.213366_x_at −0.88233 Oxidative phosphorylation
RPL23A.203012_x_at/PPIA.211765_x_at −0.88328
ACTN1.208636_at/VCL.200930_s_at −0.88344 Focal adhesion
ITGB8.205816_at/TTN.208195_at −0.88642 Focal adhesion
ITGB8.205816_at/PTN.209466_x_at −0.88642 Focal adhesion
CPT2.204264_at/ATP5C1.213366_x_at −0.89851
TTN.208195_at/PRKCB1.209685_s_at −0.90065 Focal adhesion
SDC1.201287_s_at/DDX1.201241_at −0.90504
TTN.208195_at/NEFL.221805_at −0.91592
ZNF34.219801_at/FXYD6.217897_at −0.9181
AL359052.214927_at/ATP5C1.205711_x_at −0.9188
NUCKS1.217802_s_at/PPIA.212661_x_at −0.91944
TCF7L2.212761_at/ACTN1.208636_at −0.92353 Adherens junction
TTN.208195_at/VSNL1.203798_s_at −0.93006
CASK.211208_s_at/PTN.209466_x_at −0.9301
NM_024849.220531_at/MRPL16.217980_s_at −0.93682
AJ225093.211835_at/ATP5C1.205711_x_at −0.93986
C10orf76.55662_at/PPIA.212661_x_at −0.94211
ITGB8.205816_at/SDC1.201287_s_at −0.95719 ECM-receptor interaction
ITGB8.205816_at/PPIA.212661_x_at −0.95911
CASK.211208_s_at/PPIA.211765_x_at −0.95641
TUG1.222244_s_at/SCFD1.215548_s_at −0.95643

Metafeatures are ordered by Spearman’s rank correlation with MMSE score. Genes in boldface indicate that they were previously discussed in [5] and genes with underlined boldface represent the cases for which the gene has been discussed in the context of AD in the published literature.