Table 5. Ratio metafeatures clustered with Braak staging.
| Metafeature (Gene Symbol. Probe Set ID) | Correlation Coefficient | Common KEGG Pathways |
| LRRC48.208140_s_at/SLC6A1.205152_at | 0.885391 | |
| LRRC48.208140_s_at/CHRDL1.209763_at | 0.875476 | |
| LRRC48.208140_s_at/PTN.209466_x_at | 0.868268 | |
| LRRC48.208140_s_at/PTPN4.205171_at | 0.853365 | |
| LRRC48.208140_s_at/CAST.212586_at | 0.847157 | |
| LRRC48.208140_s_at/MAOA.212741_at | 0.837757 | |
| LRRC48.208140_s_at/PPT1.200975_at | 0.837151 | |
| C16orf57.218060_s_at/RIMS2.206137_at | 0.832873 | |
| LRRC48.208140_s_at/ACO2.200793_s_at | 0.830536 | |
| LRRC48.208140_s_at/TIMM23.218118_s_at | 0.828653 | |
| LRRC48.208140_s_at/ASTN1.213197_at | 0.815831 | |
| PTTG1IP.200677_at/RANBP9.202583_s_at | 0.786333 | |
| CSF2RA.211286_x_at/BBS4.212745_s_at | 0.775829 | |
| LRRC48.208140_s_at/GABBR1.203146_s_at | 0.761019 | |
| LRRC48.208140_s_at/PRC1.218009_s_at | 0.748013 | |
| TRA@.209671_x_at/NKX3-1.209706_at | 0.673362 | |
| RHOQ.212122_at/TBCE.203715_at | 0.668935 | |
| ITGB5.201125_s_at/IFNGR2.201642_at | 0.591936 | |
| LRRC48.208140_s_at/SLC6A1.205152_at | −0.46804 | |
| CR1.206244_at/SERPINA5.209443_at | −0.66797 | Complement and coagulation cascades |
| AL520908.217833_at/LRRC48.208140_s_at | −0.68605 | |
| MDH2.213333_at/ACO2.200793_s_at | −0.76804 | TCA cycle |
| PAX6.205646_s_at/LRRC48.208140_s_at | −0.77464 | |
| SFN.33322_i_at/LRRC48.208140_s_at | −0.78278 | |
| BMX.206464_at/RGS3.220300_at | −0.82257 | |
| ITGB5.201125_s_at/TNXB.216333_x_at | −0.86804 | ECM-receptor interaction |
| C15orf39.204494_s_at/LRRC48.208140_s_at | −0.89186 |
Metafeatures are ordered by Spearman’s rank correlation with Braak staging. Genes in boldface indicate that they were previously discussed in [5] and genes with underlined boldface represent the cases for which the gene has been discussed in the context of AD in the published literature. Most of the positively correlated metafeatures in this cluster are dominated by LRRC48 (See File S2 for details).