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A. Kidneys of control rats show no positive nuclear stain for TUNEL. B–E. Kidneys from the rats with GDF treatment show a significant increase in TUNEL-positive staining after exposure to GDF at 4, 6, 9 and 12 weeks, respectively. F. The TUNEL positive staining cells of the kidney tissue were averaged for rats of each group (n = 5). Values represent means ± SD. HPF, high power field.
