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. 2012 Sep 21;7(9):e45867. doi: 10.1371/journal.pone.0045867

Table 3. Artesunate + sulfadoxine-pyrimethamine vs. praziquantel in the treatment of schistosomiasis.

Citation Year(trial) Parasite Location (Country) Study Population (age) Time point analysed (weeks) Treatment N°Cured/N° Treated
Sissoko et al., 2009 [32] 2007 S. haematobium Bamako (Mali) Children (6–15) 4 ART+SP1 172/392
PZQ2 206/389
Mohamed et al., 2009 [51] 2008 S. mansoni New Halfa (Sudan) Children (8–17) 4 ART+SP3 27/46
PZQ2 46/46
Obonyo et al., 2010 [33] 2009 S. mansoni Rarieda (Kenya) Children (6–15) 4 ART+ SP4 15/106
PZQ2 69/106
1

ART: (artesunate 100 mg/day) + S (sulfadoxine 250 mg/day) + P (pyrimethamine 12.5 mg/day) over three days;

2

PZQ (praziquantel 40 mg/kg once);

3

ART (artesunate 4 mg/kg/day over three days) + SP (sulfadoxine-pyrimethamine 25mg/kg );

4

ART(artesunate 4 mg/kg/day over three days) + S (sulfadoxine 25mg/kg) + P (pyrimethamine 12.5 mg/day).