Table 3. Predictive associations (odds-ratios) along with 95% confidence intervals (95% CI) of number of lifetime estimated DSM-IV disorders with the subsequent first onset of other estimated DSM-IV disorders based on the best-fitting multivariate survival model (n = 6,483)^a.

	Number of predictor disorders
	2		3		4		5		6		7+
Outcome disorders	OR	(95% CI)	OR	(95% CI)	OR	(95% CI)	OR	(95% CI)	OR	(95% CI)	OR	(95% CI)
I. Fear disorders
Specific phobia	1.0	0.5-2.0	0.3	0.1-1.1	0.9	0.2-4.9	0.7	0.1-7.0	1.2	0.1-11.4	3.6	0.3-45.5
Agoraphobiab	0.6	0.2-1.7	0.4	0.0-2.4	0.4	0.0-3.8	0.1	0.0-2.0	0.0*	0.0-0.8	0.0	0.0-6.4
Social phobia	0.8	0.4-1.9	0.6	0.2-2.0	0.4	0.1-2.7	0.1	0.0-1.5	0.1*	0.0-0.7	1.0	0.0-65.5
Panic disorderc	0.9	0.4-2.2	1.1	0.2-6.7	0.4	0.0-7.6	0.3	0.0-6.4	0.4	0.0-14.1	0.0	0.0-5.1
II. Distress disorders
Separation anxiety disorder	0.7	0.3-1.6	1.0	0.3-3.2	0.9	0.2-4.7	0.7	0.1-5.4	0.0*	0.0-0.2	1.8	0.1-51.6
Post-traumatic stress disorder	0.7	0.3-1.6	0.6	0.1-2.3	0.1*	0.0-0.3	0.1*	0.0-0.7	0.1	0.0-1.7	0.0*	0.0-0.4
Major depressive disorder/dysthymia	0.8	0.4-1.3	0.4*	0.2-0.8	0.2*	0.1-0.6	0.1*	0.0-0.2	0.1*	0.0-0.4	-	-
Generalized anxiety disorder	1.0	0-.33.6	0.9	0.1-5.5	0.7	0.1-9.0	0.2	0.0-3.5	0.2	0.0-8.8	0.0	0.0-28.6
III. Behavior disorders
Attention-deficit/hyperactivity disorder	1.2	0.3-5.1	3.0	0.3-30.2	0.6	0.0-15.3
Oppositional defiant disorder	0.8	0.4-1.6	0.6	0.3-1.2	0.2*	0.0-0.9	0.1*	0.0-0.8	0.0*	0.0-0.4	0.0*	0.0-0.5
Conduct disorder	1.0	0.5-2.4	0.4	0.1-1.2	0.4	0.6-2.0	0.2	0.0-1.3	0.1	0.0-1.0	0.2	0.0-9.6
Eating disordersd	0.8	0.3-2.1	0.3*	0.1-0.8	0.2	0.0-1.2	0.2	0.0-1.4	0.1	0.0-1.3	0.0*	0.0-0.04
IV. Substance disorders
Alcohol abusee	0.6	0.2-1.8	0.6	0.1-2.8	0.3	0.0-2.2	0.1*	0.0-0.9	0.0*	0.0-0.4	0.0	0.0-1.6
Drug abusee	0.9	0.4-1.9	0.4	0.2-1.3	0.2*	0.0-1.0	0.1*	0.0-1.0	0.3	0.0-4.6	0.0*	0.0-0.4
V. Other disorders
Bipolar disorderf	0.4*	0.2-0.8	0.2*	0.1-0.6	0.2	0.0-0.7	0.0*	0.0-0.3	0.0*	0.0-0.02	0.0*	0.0-0.02

^*Significant at the .05-level, two-sided test

^aBased on a discrete-time (person-year) survival model in which first lifetime onset of each of the 15 estimated DSM-IV disorders is predicted by 14 dummy variables for prior lifetime history of the other disorders, dummy variables for number of prior lifetime disorders (2-7+), and socio-demographic controls (sex, race/ethnicity, region of the country, urbanicity, parent education, number of biological parents with whom the adolescent lives, birth order, number of siblings, and age).

^bAgoraphobia is assessed with or without panic disorder

^cPanic Disorder is assessed with or without agoraphobia

^dIncludes anorexia nervosa, bulimia nervosa, and binge-eating disorder

^eWith or without dependence

^fincludes Bipolar-I, Bipolar-II, and sub-threshold bipolar disorder