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. 2012 Oct;26(10):4230–4242. doi: 10.1096/fj.12-207969

Figure 5.

Figure 5.

Injection of actn2 MO leads to reduced cardiac function. A) Injection of actn2 MO reduces the shortening fraction, which is rescued by transgenic actn2 in Tg(ttna:actn2-egfp) fish. B) End-diastolic diameter is reduced in actn2 morphants. C) End-systolic diameter is comparable between WT fish and actn2 morphants. D) Heart rate is not affected by injection of actn2 MO. MO, actn2 MO fish; Tg, Tg(ttna:actn2-egfp) fish; MO+Tg, Tg(ttna:actn2-egfp) fish injected with actn2 MO; n, fish number; NS, not significant. *P < 0.05.