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. Author manuscript; available in PMC: 2013 Oct 1.
Published in final edited form as: J Immunol. 2012 Aug 22;189(7):3734–3740. doi: 10.4049/jimmunol.1200136

Figure 1.

Figure 1

Inflammation to necrotic cells after 4 hour of injection to peritoneal cavity. The total neutrophil (A) and monocyte(B) numbers in peritoneal cavity of WT C57BL/6, caspase-1-deficient, cathepsin C-deficient, caspase-1 and cathepsin C double-deficient, IL-1β-deficient and IL-1R-deficient mice after 4 hours i.p. injection of 10 million of heat-shocked necrotic EL4 cells. The data are combined results of 4 experiments and represented as means ± SEM (n = total number of mice from the multiple experiments for each group). * P<0.05, **P<0.01, NS, not significant versus WT groups using ANOVA with Dunnett's multiple camparison tests. PBS groups, WT mice received i.p. PBS.