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. Author manuscript; available in PMC: 2013 Oct 1.
Published in final edited form as: J Immunol. 2012 Aug 29;189(7):3669–3680. doi: 10.4049/jimmunol.1103180

Figure 5.

Figure 5

Levels of expression of transcripts related to the Th2 cytokine response during muscle unloading and reloading. Expression levels of CD163 (A), IL-10 (B), IL-10R1 (C) and Arg-1 (D) were all elevated at 4-days of reloading in wild-type muscles, reflecting a Th2 cytokine response, although HMOX-1 (E) was not elevated at that stage. Null mutation of IL-10 attenuated the Th2 cytokine response at 4-days of reloading, reflected in significant reductions of CD163 and Arg-1. * indicates significantly different from ambulatory control muscle of same genotype at p < 0.05. § indicates significantly different from wild-type muscle under the same treatment conditions at p < 0.05. # indicates significantly different from 1-day reloaded muscle of same genotype at p < 0.05. Each bar represents the mean and sem for the muscles collected from 6 mice in each data set. All data in each set were normalized relative to expression levels in ambulatory, wild-type muscles which were set at 1.0.