Scheme 4.
Derivatization of the C3-amine.
Reagents and conditions: i. HCl/dioxane. For compounds 7a and 7b: ii. C7H15CHO, CH3COOH, NaCNBH3, MeOH. For compound 7c: iii. (CF3CO)2O, CH2Cl2.
Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.