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. Author manuscript; available in PMC: 2012 Sep 25.
Published in final edited form as: J Am Coll Cardiol. 2012 Jul 18;60(13):1173–1181. doi: 10.1016/j.jacc.2012.04.030

Table 5.

Genetic association of rare variants alone (ignoring common variants) un-stratified and stratified by age of onset and age of unaffected individuals in the families.

Sample size Presence/absence of
rare variants only
(P-value)		 OR (95% CI)
Un-stratified 70 2.2 × 10−4 19 (2.4–155)
Age of onset<50yrs 64 0.003 14 (1.7–117)
Age of onset<40 yrs 57 0.04 8.8 (1.1–74)
Unaffected age>50 yrs 48 2.1 × 10−4 26 (3.0–227)
Age of onset<50 yrs
Unaffected age>50 yrs		 42 0.002 20 (2.2–173)
Age of onset<40 yrs
Unaffected age>50 yrs		 35 0.013 12 (1.3–109)