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. Author manuscript; available in PMC: 2012 Sep 25.
Published in final edited form as: J Am Coll Cardiol. 2012 Jul 18;60(13):1173–1181. doi: 10.1016/j.jacc.2012.04.030

Table 6.

Genetic association of common variants in the subset of data with all individuals harboring rare variants: un-stratified and stratified by age of onset and age of unaffected individuals in the families.

Sample size Common variants in individuals
with rare variants only (P-value)
Un-stratified 48 2.79 × 10−7
Age of onset <50 yrs 42 4.41 × 10−6
Age of onset <40 yrs 36 1.46 × 10−4
Unaffected age >50 yrs 34 3.4 × 10−4
Age of onset <50 yrs,
Unaffected age >50 yrs
28 0.001
Age of onset <40 yrs,
Unaffected age >50 yrs
22 0.01