Table 2.

Structure analysis of computationally docked nutlin-like inhibitors

Record number	Drug Name	Number of drug atoms involved in MDM2 contacts	Number of hydrogen bond contacts to MDM2	Number of MDM2 amino acids bound to drug	Percentage of nutlin 3a-CM binding amino acids
	nutlin 3a-CM	15	0	9	100
ZINC03830283	S-bepridil/Vascor	14	0	10	67
ZINC03831395	Protirelin/Thyrel TRH	9	2	7	55
ZINC11677473	Azaribine/Triazure	10	1	8	44
ZINC01847743	caramiphen, Ordrine AT	13	0	9	67
ZINC03812918	R-bepridil/Vascor	16	0	10	78
ZINC00001446	Prenazone, Feprazone	10	0	9	67
ZINC00537935	Lorcainide hydrochloride	12	0	7	67
ZINC00607836	Doxapramhydrochloride/Dopram	14	0	8	55
ZINC01530778	Phenylbutazone	11	0	9	55
ZINC03831172	Nafronyl-d4	17	1	7	55
ZINC04026871	nandrolone phenylpropionate	15	0	8	55
ZINC00601229	Azelastine	13	0	7	44
ZINC00000452	Mephenoxalone	8	0	5	44
ZINC04534031	Azlocillin	12	0	7	44
ZINC00001732	Midazolam hydrochloride	10	0	7	55