Table 1.
Basal values of MAP and HR of non-conditioned and conditioned animals after treatment with adrenoceptor antagonists or vehicle
| Group | N (animals) | MAP (mmHg) | HR (bpm) | Temperature (°C) |
|---|---|---|---|---|
| Non-conditioned | ||||
| Vehicle | 6 | 93 ± 2 | 344 ± 13 | 31.9 ± 1.3 |
| L-prop, 7.5 nmol | 6 | 98 ± 3 | 349 ± 18 | 31.2 ± 0.9 |
| L-prop, 12.5 nmol | 6 | 97 ± 4 | 387 ± 16 | 31.7 ± 1.1 |
| F2,12= 0.8 | F2,12= 1.9 | F2,17= 0.1 | ||
| Vehicle | 5 | 102 ± 5 | 360 ± 24 | 30.8 ± 2.3 |
| Phento, 10 nmol | 7 | 109 ± 6 | 366 ± 18 | 31.5 ± 1.2 |
| Phento, 20 nmol | 7 | 104 ± 2 | 357 ± 22 | 30.6 ± 0.6 |
| F2,12= 0.5 | F2,12= 0.03 | F2,18= 0.13 | ||
| Vehicle | 5 | 102 ± 5 | 360 ± 24 | 32 ± 0.6 |
| L-prop, 7.5 nmol + Phento, 10 nmol | 7 | 107 ± 6 | 359 ± 23 | 31.8 ± 0.8 |
| t= 0.67 | t= 0.05 | t= 0.18 | ||
| Conditioned | ||||
| Vehicle | 8 | 94 ± 2 | 328 ± 9 | 31.1 ± 0.4 |
| L-prop, 7.5 nmol | 8 | 110 ± 8 | 351 ± 7 | 31.8 ± 1.1 |
| L-prop, 12.5 nmol | 8 | 105 ± 3 | 350 ± 10 | 30.5 ± 0.7 |
| OUT | 5 | 95 ± 2 | 318 ± 11 | 31.5 ± 0.9 |
| F3,18= 2.8 | F3,18= 2.9 | F3,27= 0.5 | ||
| Vehicle | 7 | 95 ± 2 | 324 ± 9 | 31.7 ± 1 |
| Phento, 10 nmol | 8 | 102 ± 2 | 371 ± 15 | 32.1 ± 0.7 |
| Phento, 20 nmol | 8 | 99 ± 3 | 348 ± 11 | 31 ± 1.1 |
| OUT | 4 | 96 ± 2 | 342 ± 10 | 31.5 ± 0.9 |
| F3,19= 1.5 | F3,19= 2.5 | F3,26= 0.25 | ||
| Vehicle | 7 | 98 ± 2 | 349 ± 6 | 32 ± 0.4 |
| L-prop, 7.5 nmol + Phento, 10 nmol | 8 | 99 ± 5 | 377 ± 9 | 31.6 ± 0.8 |
| t= 0.15 | t= 2.6 | t= 0.42 |
The values in the table represent the means ± SEM. No significant difference in the values within each group was observed;. one-way anova. L-prop, L-propranolol; Phento, phentolamine.