. 2012 Dec 1;17(11):1507–1514. doi: 10.1089/ars.2011.4470

Table 1.

List of Proteins with Differential Levels in M631L Transgenic Mice Relative to M631 Non-Transgenic controls

Protein	Swiss Prot no.	MW (kDa)	pI	Peptides (SC)^a	P^b	Fold change^c	p-Value^d
Hsp90 B1	P08113	92.42	4.59	4 (8)	5.00e⁻⁰⁶	2.28↑	0.035
Proteasome subunit β, type 2	Q9R1P3	22.89	6.61	1 (2)	3.00e⁻⁰⁴	1.65↓	0.019

^{^a}

The number of peptide sequences identified by nanospray ESI-MS/MS of tryptic peptides. The total number of MS/MS spectral counts is indicated in parenthesis.

^{^b}

The probability of an incorrect identification associated with each protein identification using the SEQUEST search alogorithm.

^{^c}

The fold change in spot density from M631L Tg mice compared with M631 NTg controls. The arrow indicates the direction of change.

^{^d}

The P-value associated with fold change^c calculated using a Student's t-test. n=10 for M631L Tg, n=5 for M631 NTg.

ESI, electrospray ionization; Leu/L, leucine; Met/M, methionine; MS, mass spectrometry; MW, molecular weight; NTg, non-transgenic; P, probability of type I error; pI, isoelectric point; SC, spectral counts; Tg, transgenic.