Table 2.
Patient No. | Strain No. | spa Type | spa Motif | CCa | δ-Hemolysin | agr Mutationb | Predicted Result |
---|---|---|---|---|---|---|---|
167 | 211 | 43 | WGKAKAOMQ | 30 | + | No mutation found | None |
70 | 81 | 33 | WGKAKAOMQQ | 30 | + | No mutation found | None |
119 | 146 | 16 | WGKAKAOMQQQ | 30 | + | No mutation found | None |
56 | 57 | 19 | XKAKAOMQ | 30 | + | No mutation found | None |
122 | 149 | 1384 | WGKAKAOLOMQQ | 30 | Weak | g272a | Ser>Asn at aa 91 AgrCc |
163 | 204 | 43 | WGKAKAOMQ | 30 | Weak | t487g | Ser>Ala at aa 163 AgrCd |
33 | 22 | 43 | WGKAKAOMQ | 30 | Weak | No mutation found | None |
80 | 95 | 43 | WGKAKAOMQ | 30 | Weak | No mutation found | None |
89 | 109 | 43 | WGKAKAOMQ | 30 | Weak | No mutation found | None |
92 | 105 | 43 | WGKAKAOMQ | 30 | Weak | No mutation found | None |
15 | 3 | 33 | WGKAKAOMQQ | 30 | Weak | No mutation found | None |
72 | 84 | 33 | WGKAKAOMQQ | 30 | Weak | No mutation found | None |
75 | 88 | 33 | WGKAKAOMQQ | 30 | Weak | No mutation found | None |
87 | 102 | 33 | WGKAKAOMQQ | 30 | Weak | No mutation found | None |
94 | 112 | 33 | WGKAKAOMQQ | 30 | Weak | No mutation found | None |
103 | 122 | 33 | WGKAKAOMQQ | 30 | Weak | No mutation found | None |
109 | 129 | 33 | WGKAKAOMQQ | 30 | Weak | No mutation found | None |
118 | 144 | 33 | WGKAKAOMQQ | 30 | Weak | No mutation found | None |
131 | 159 | 33 | WGKAKAOMQQ | 30 | Weak | No mutation found | None |
154 | 190 | 33 | WGKAKAOMQQ | 30 | Weak | No mutation found | None |
40 | 40 | 16 | WGKAKAOMQQQ | 30 | Weak | No mutation found | None |
96 | 114 | 16 | WGKAKAOMQQQ | 30 | Weak | No mutation found | None |
157 | 194 | 19 | XKAKAOMQ | 30 | Weak | No mutation found | None |
30 | 19 | 532 | WGKAKAOM | 30 | − | No mutation found | None |
73 | 85 | 33 | WGKAKAOMQQ | 30 | − | t224a | Ile>Asn at aa 75 in AgrAc |
110 | 130 | 33 | WGKAKAOMQQ | 30 | − | t485c | Phe>Ser at aa 162 in AgrCc |
Abbreviations: −, negative; +, positive; aa, amino acid.
a spa-type-deduced CC. Primary grouping of strains is by agr functionality, followed by polymorphism of spa.
b Designation corresponds to the region in agrC or agrA of genome-sequenced CC30 prototype strain MRSA252, which has an AgrC G55R amino acid change that attenuates agr function (see text).
c Not tolerated by the sorting intolerant from tolerant (SIFT) algorithm.
d Tolerated by the SIFT algorithm.