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. 2012 Aug 28;206(8):1206–1217. doi: 10.1093/infdis/jis492

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Published by Oxford University Press on behalf of the Infectious Diseases Society of America 2012.

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Figure 1. — Interleukin 17 (IL-17) expression in macrophages from patients with AIDS who were coinfected with human immunodeficiency virus-1 (HIV-1) and Mycobacterium avium complex (MAC). A, Representative lymph node tissue sections from 3 individuals coinfected with MAC and HIV-1 show IL-17 protein detected by immunohistochemical analysis. B, Lymph node tissue sections for 2 individuals positive only for HIV show minimal IL-17 protein. C, Lymph node tissue sections from 3 individuals coinfected with MAC and HIV-1 show massive numbers of CD68⁺ macrophages, reflecting similar pattern as IL-17 staining. The inset shows detection of MAC (red) in coinfected lymph nodes, as described in Materials and Methods. D, No staining was observed with an isotype-matched control antibody (coinfected tissue shown). Original magnification in all panels is 63×.