Table 1.
Baseline clinical characteristics of the offspring vs. partners of the offspring according to gender
| Variables | Female (N = 339) | Male (N = 333) | ||
|---|---|---|---|---|
| Offspring (N = 153) | Partners (N = 186) | Offspring (N = 183) | Partners (N = 150) | |
| Age, years (mean, SD) | 62.9 (5.9) | 60.7 (6.9) | 63.6 (6.0) | 65.4 (6.9) |
| Comorbidities (%) | 34.1 | 42.1 | 37.3 | 46.3 |
| Myocardial infarct | 0.0 | 1.2 | 2.4 | 6.1 |
| Stroke | 0.7 | 2.4 | 4.3 | 3.0 |
| Hypertension | 27.8 | 31.1 | 24.8 | 30.5 |
| Diabetes mellitus | 3.1 | 6.7 | 4.9 | 14.6 |
| Neoplasm | 6.8 | 8.5 | 7.3 | 7.0 |
| Chronic obstructive pulmonary disease | 2.3 | 4.2 | 6.7 | 3.1 |
| Rheumatoid arthritis | 0.7 | 1.2 | 0.6 | 1.5 |
| Sum score of comorbidities (median, IQR) | 0 (0–1) | 0 (0–1) | 0 (0–1) | 0 (0–1) |
| Medication categories (%) | ||||
| Cardiovascular | 30.9 | 31.2 | 24.6 | 46.7 |
| Anti-thrombotic | 5.1 | 6.5 | 10.5 | 18.5 |
| Chronic obstructive pulmonary disease | 5.1 | 5.9 | 4.1 | 1.5 |
| Anti-diabetics | 2.2 | 4.7 | 3.5 | 10.4 |
| Other endocrine medications | 8.1 | 5.9 | 0.6 | 2.2 |
| Nervous system | 19.9 | 14.7 | 9.4 | 12.6 |
| Sum score of medication categories (median, IQR) | 0 (0–1) | 0 (0–1) | 0 (0–1) | 1 (0–2) |
| Current smoking (%) | 7.4 | 15.6 | 13.8 | 13.1 |
| Excessive alcohol use (%) | 12.8 | 16.1 | 27.5 | 30.1 |
| Thyroid function | ||||
| TSH, mU/l (median, IQR) | 1.8 (1.1–2.7) | 1.6 (1.1–2.3) | 1.6 (1.2–2.1) | 1.5 (1.1–2.1) |
| fT3, pmol/l (mean, SD) | 3.9 (0.7) | 4.0 (0.7) | 4.3 (0.7) | 4.2 (0.6) |
| fT4, pmol/l (mean, SD) | 15.3 (2.5z) | 15.0 (2.6) | 15.5 (2.3) | 15.6 (1.9) |