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Time constant constraints. Constraint set A was applied to parameter sets 6–8 in Table 1 (see Figure 5, panels b–d), and sets A, B, and C were all applied to parameter set 1 in Table 1 (Figure 5, panel a). Constraint set D was used alongside parameter set 1 in Table 1 in a Monte Carlo simulation to validate CRLB calculations (Figure 2).
| Constraint Set | T2,S (ms) | T2,F (ms) | kFS (s−1) |
|---|---|---|---|
| A | 150 | 20 | 10 |
| B | 100 | 30 | 10 |
| C | 100 | 20 | 15 |
| D | 125 | 35 | 5 |
