Figure 7.
Pretreatment with a GABAB agonist reduces EtOH potentiation of sIPSC frequency. Top, sIPSCs recorded from a representative cell during 1 μM baclofen pretreatment and during baclofen + EtOH conditions. Bottom, bar graph summarizing the effect of EtOH alone and following pretreatment with 1 μM baclofen on sIPSC frequency, amplitude, and decay. Numbers in parentheses represent the number of cells tested under each experimental condition.*, significant difference from control conditions (p < 0.05). #, significant difference between groups (p < 0.05).