Table 3. Pearson's correlations of CC volumes with selected neurocognitive measures in children with 22q11DS (n=59, trails B time data available only for 25 subjects).
CC region | Verbal comprehension | Working memory | Trails B time | WCST perseverative errors | WIAT math score |
---|---|---|---|---|---|
Genu | 0.20 | 0.17 | −0.46* | 0.11 | 0.09 |
Posterior Genu | 0.24 | 0.06 | −0.32 | 0.13 | 0.10 |
Truncus | 0.21 | 0.01 | −0.34 | 0.10 | 0.07 |
Anterior Splenium | 0.21 | 0.10 | −0.27 | 0.24 | 0.03 |
Splenium | 0.35** | 0.30* | −0.46* | 0.36** | 0.28* |
Total CC | 0.33* | 0.28* | −0.50* | 0.26* | 0.17 |
Negative correlation with trails B time indicated that increased CC volumes were associated with a shorter time required to complete the task, so if effect these are positive correlations with set-shifting.
Magnitude of correlation: 0.1=small, 0.3=medium and 0.5=large. Medium and large effect sizes are in bold.
P<0.05.
P<0.01.