. Author manuscript; available in PMC: 2012 Sep 23.

Published in final edited form as: Arch Pathol Lab Med. 2012 Apr;136(4):372–390. doi: 10.5858/arpa.2011-0471-RA

Table 2.

Immunohistochemistry Expression of ERG Protein Strongly Correlates With TMRSS2-ERG Fusion Regardless of Mechanism of Fusion^a

FISH	No. Cases	No ERG Expression, No. (%)	ERG Expression, No. (%)	P
Esplit				<.001
	108	17 (15.7)	91 (84.3)
	319	218 (68.3)	101 (31.7)
Edel				<.001
	158	21 (13.3)	137 (86.7)
	269	214 (79.6)	55 (2.4)
2Esplit				.008
	6	0 (0)	6 (100)
	421	235 (55.8)	186 (44.2)
2Edel				<.001
	24	1 (4.2)	23 (95.8)
	403	234 (58.1)	169 (41.9)
Any fusion				<.001
	195	28 (14.4)	167 (85.6)
	232	207 (89.2)	25 (10.8)

Abbreviations: Edel, deletion; Esplit, insertion leading to FISH signal split; FISH, fluorescence in situ hybridization.

Reprinted from Chaux et al¹⁹³ with permission from Lippincott Williams & Wilkins.