TABLE 1.

Biomarker Expression in Xp11 Translocation RCC Relative to Clear Cell RCC and Papillary RCC

	Xp11 Translocation RCC (21 Cases)		Clear Cell RCC (7 Cases)		Papillary RCC (6 Cases)
Marker	% Cases Positive	Mean % Labeling	% Cases Positive	Mean % Labeling	% Cases Positive	Mean % Labeling
PAX2*	66	45	72	56	100	37
PAX8*	76	58	72	61	100	67
MiTF*	5	5	0	0	0	0
HIF-1α†	24‡	22	43‡	39	0‡	0
CA IX†	57	5.7	100	100	66	1.8
HIG-2†	100	42	100	61	83	11
Napsin A†	43	10	43	8.5	83	31
EpCAM*	43	23	28	5	100	34
Claudin 7*	33	31	14	30	100	70
Ksp-Cadherin*	14	40	0	0	0	0
pS6†	90	32.6	67	23	83	17
p21*	24	26	14	90	33	17
Bcl2*	24	26	57	37	0	0
WT-1†	0	0	0	0	0	0
CD117†	0	0	0	0	0	0
ER†	0	0	0	0	0	0

Note that the calculated H score is given in the text for pS6.

^*Mean calculated among positive cases.

^†Mean calculated among all cases.

^‡Diffusely positive cases.

pS6 indicates phosphorylated S6.