Figure 2. Effect of Src inhibition results on apoptosis and cell cycle regulation.
(A) There was a concentration-dependent decrease in percentage of cells in G2-M and S phases starting at 10 nmol/L of dasatinib in BxPC3 cells and starting at 50 nmol/L in PANC1 cells. (B) There was a concentration-dependent induction of apoptosis by Caspase-Glo 3/7 assay starting at 5 nmol/L in BxPC3 cells and starting at 100 nmol/L in PANC1 cells. Each condition was assayed in triplicate and the means ± SD are presented. Standard error: *p<0.05; **p<0.01; ***p<0.001; ns=p>0.05.