Figure 3. Effect of Src inhibition on migration, invasion and colony formation.
Concentration-dependent decrease in cell migration (A), invasion (B) and colony formation (C) were seen. BxPC3 cells were significantly more sensitive at any concentration studied when compared with more resistant PANC1 cells. Individual data point represent the mean ± SD of three independent experiments. (D) Inhibition of Src expression by shRNA decreases migration and invasion in BxPC3 cells. Each data point represents the mean ± SD of triplicate plates. *p<0.05; **p<0.01; ***p<0.001; ns=p>0.05.