Average empirical FDR, FNR, ATP and AUROC for various signal levels μk at nominal FDR of 0.10. Column 1 compares the empirical FDR versus μk. Column 2 compares the empirical FNR versus μk. Column 3 compares the ATP versus μk. Column 4 compares the AUROC versus μk. Rows 1, 2 and 3 correspond to non-null proportion of 0.05, 0.1 and 0.2, respectively. HMM-kernel density estimate (○), HMM-Gaussian mixtures (△), HMM-symmetric kernel density estimate (+), BH (×) and locfdr (◇).