Table 1.

Absolute tension, pD₂ and E_max in various conditions

		ACh
Conditions	PGF2α (mN mm−1)	pD2	Emax	n
1
Endothelium (+)	0.74 ± 0.13	8.6 ± 0.1	93.1 ± 3.7	7
Endothelium (−)	0.81 ± 0.15	N.D	2.8 ± 6.4***	7
2
None	0.88 ± 0.10	8.6 ± 0.1	96.3 ± 1.4	7
l -NNA	1.09 ± 0.15	8.1 ± 0.1***	88.7 ± 3.4	7
l -NNA + diclofenac	1.07 ± 0.15	7.9 ± 0.1***	90.7 ± 3.9	7
3
None	0.76 ± 0.21	8.9 ± 0.1	92.3 ± 5.1	7
l -NNA + diclofenac	0.80 ± 0.17	7.5 ± 0.3*	87.2 ± 2.7	7
l -NNA + diclofenac + apamin + charybdotoxin	1.22 ± 0.32†	N.D.	−7.9 ± 17.5**††	7
4
l -NNA + diclofenac	0.99 ± 0.10	7.3 ± 0.1	81.8 ± 0.04	7
l -NNA + diclofenac + apamin + TRAM 34	1.13 ± 0.13	6.6 ± 0.2†	62.9 ± 0.05††	7
l -NNA + diclofenac + apamin + TRAM 34 + margatoxin	1.22 ± 0.22	6.6 ± 0.2†	33.0 ± 0.09†††#	7

The concentration of PGF_2α was 3 µM in endothelium-intact strips not treated with l -NNA but 1 µM in endothelium-intact strips treated with l -NNA and in endothelium-denuded preparations. *, **, ***P < 0.05, 0.01, 0.001 vs. ‘Endothelium (+)’ or ‘None’. ^†, ^††, ^†††P < 0.05, 0.01, 0.001 vs. ‘l -NNA + diclofenac’. ^#P < 0.05 vs. ‘l -NNA + diclofenac + apamin + TRAM 34’.