TABLE 2.
Demographic data stratified by presence or absence of postoperative CSF leak
| Characteristic | No. of Cases (%)
|
||
|---|---|---|---|
| No Postop CSF Leak (n = 83) | Postop CSF Leak (n = 13) | p Value* | |
| mean age in yrs (range) | 54.6 (19.8–88.2) | 42.9 (22.4–73.5) | 0.004 |
| male sex | 43 (51.8) | 3 (23.1) | 0.074 |
| mean BMI in kg/m2 (range) | 32.9 (18.9–61.8) | 39.2 (26.2–55.6) | 0.006 |
| diagnosis | |||
| pituitary adenoma | 76 (91.6) | 12 (92.3) | 1.000 |
| connective tissue/infection | 4 (4.8) | 0 (0.0) | 1.000 |
| Rathke cleft cyst | 2 (2.4) | 1 (7.7) | 0.357 |
| metastatic lesion | 1 (1.2) | 0 (0.0) | 1.000 |
| Cushing disease | 4 (4.8) | 1 (7.7) | 0.525 |
| mean mass vol in cm3 (range) | 7.0 (0.0–57.6) | 4.4 (0.0–17.2) | 0.132 |
| sella/suprasellar remnant | 43 (51.8) | 4 (30.7) | 0.234 |
| cavernous remnant | 20 (24.1) | 2 (15.4) | 0.726 |
| sphenoid packing | 19 (22.9) | 7 (53.8) | 0.039 |
| intraop lumbar drain/puncture | 0 (0.0) | 1 (7.7) | 0.135 |
| repeat transsphenoidal surgery | 5 (6.0) | 2 (15.4) | 0.240 |
| intraop leak | 32 (38.6) | 9 (69.2) | 0.067 |
*
Wilcoxon rank-sum tests (continuous variables) and Fisher exact tests (dichotomous variables) were used to compare the no postoperative CSF leak group with the postoperative CSF leak group.