Table 1.

Symptoms frequently found in FXS patients sorted by domains.

Domain	Symptoms frequently found in FXS patients
Behavior	Pervasive hyperactivity and impulsivity (Bregman et al., 1988; Baumgardner et al., 1995; Schneider et al., 2009)
	Stereotyped behavior, self injury, perseverative preoccupations, and interest (Bregman et al., 1988)
	Poor fine and gross motor coordination (Loesch et al., 2003)
	Delayed socialization and avoidance (Budimirovic et al., 2006)
Social cognition	Gaze aversion (Bregman et al., 1988; Schneider et al., 2009)
	Impaired face recognition and emotion perception (Turk and Cornish, 1998)
	Theory of mind (Garner et al., 1999)
Language	Delayed echolalia (Bregman et al., 1988; Cornish et al., 2005; Schneider et al., 2009)
	Idiosyncratic responses (Bregman et al., 1988)
	Abnormalities in intonation and rhythm (Bregman et al., 1988)
	Verbal perseveration (Bregman et al., 1988; Schneider et al., 2009)
	Cluttering of speech (Cornish et al., 2005)
	Tangential language (Sudhalter and Belser, 2001)
Executive functions	Working memory (Cornish et al., 2005, 2008; Schneider et al., 2009)
	Planning and set shifting (Schneider et al., 2009)
	Deficits in attentional control (Bregman et al., 1988; Cornish et al., 2005)
	Inhibition (Cornish et al., 2005)
	Sequential processing (Loesch et al., 2003)
Emotional stability	Anxiety disorders (Bregman et al., 1988; Cornish et al., 2005; Schneider et al., 2009)
	Social avoidance (Cornish et al., 2005; Schneider et al., 2009)
	Aggression (Schneider et al., 2009)
Visual-spatial cognition	Impairments in visual-spatial reasoning (Cornish et al., 2008; Schneider et al., 2009)
	Object occlusion (Farzin and Rivera, 2010) Arithmetic problems (Loesch et al., 2003)
Hyperarousal	Hyperarousal to sensory stimuli (Schneider et al., 2009)