Table 3.

Proteins in Ts1Cje Transgenic Mice (DS Model) Modified by HNE and 3-Hydroperoxy-9Z,11E-Octadecadienoic Acid

	Protein	Function
Proteins HNE-bound	Neurofilament light polypeptide	Cytoskeletal integrity
	Internexin neuronal filament	Cytoskeletal integrity
	Prx VI	Antioxidant defense
	PGK1	Energy metabolism
	TPI	Energy metabolism
Proteins 13-HPODE-modified	TPI	Energy metabolism
	α-Enolase	Energy metabolism
	ATP synthase	Energy metabolism
		Mitochondrial function

13-HPODE, 3-hydroperoxy-9Z,11E-octadecadienoic acid.