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The biodistribution of different formulations in tumors and normal tissues.
Notes: At 24 hours after injection, the DOX concentration was measured by an Agilent 1200 FLD fluorescence detector. The DOX concentration inside tumor tissue in M-PLDU group was higher than that in FD and PLDU groups (n = 4 in each group; *P < 0.05, **P < 0.01).
Abbreviations: DOX, doxorubicin; FD, free doxorubicin.
