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. 2011 Jun 15;22(3):584–594. doi: 10.1093/cercor/bhr131

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© The Author 2011. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com

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Figure 7. — PKA-dependent tonic control of mEPSCs frequency. (A₁) Bath application of forskolin (20 μM) enhanced mEPSC frequency. (A₂) Pretreatment of slices with and continuous bath application of KT5720 (1 μM) counteracted forskolin-induced enhancement of mEPSC frequency. (B₁) Bath application of IBMX (500 μM) significantly increased mEPSC frequency. (B₂) Pretreatment of slices with and continuous bath application of KT5720 (1 μM) blocked IBMX-induced enhancement of mEPSC frequency. (C) Bath application of KT5720 (1 μM) reduced mEPSC frequency. (D) Bath application of MDL-12,330A (50 μM) inhibited mEPSC frequency.